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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WASL All Species: 21.82
Human Site: S145 Identified Species: 36.92
UniProt: O00401 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00401 NP_003932.3 505 54827 S145 L G R R Q R K S E K R R D P P
Chimpanzee Pan troglodytes XP_001148606 495 53819 S135 L G R R Q R K S E K R R D P P
Rhesus Macaque Macaca mulatta XP_001085180 435 47267 P129 T T N R F Y G P Q V N N I S H
Dog Lupus familis XP_532445 505 54680 S145 L G R R Q R K S E K R R D P P
Cat Felis silvestris
Mouse Mus musculus Q91YD9 501 54256 S142 L G R R Q R K S E K R R D A P
Rat Rattus norvegicus O08816 501 54307 S142 L G R R Q R K S E K R R D A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508405 466 50516 N136 I T T N R F Y N P Q V N N I S
Chicken Gallus gallus XP_415994 505 54715 S145 L G R R Q R K S E K I R D P P
Frog Xenopus laevis NP_001084852 512 55702 K148 L I A R R P R K P D K K R E P
Zebra Danio Brachydanio rerio Q6PFT9 646 70983 L280 K E K D K E Q L L E E N F C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651637 527 56956 Q148 E T R N R K R Q E K R N R Q K
Honey Bee Apis mellifera XP_392742 528 58877 A155 E G E T Q H G A T L P W R N Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181262 492 52224 H143 M S S I Y Q P H G G A H N T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12446 633 67553 N170 D N Q R K R Y N Y E D V D T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 85.5 97 N.A. 95.4 95.2 N.A. 86.1 91.2 74.4 20.1 N.A. 35.6 34.8 N.A. 38.4
Protein Similarity: 100 98 85.7 98 N.A. 96.8 96.8 N.A. 87.3 94 83.4 31.4 N.A. 49.7 51.1 N.A. 51.4
P-Site Identity: 100 100 6.6 100 N.A. 93.3 93.3 N.A. 0 93.3 20 0 N.A. 26.6 13.3 N.A. 0
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 33.3 93.3 46.6 26.6 N.A. 46.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 0 0 8 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 8 8 0 50 0 0 % D
% Glu: 15 8 8 0 0 8 0 0 50 15 8 0 0 8 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 50 0 0 0 0 15 0 8 8 0 0 0 0 8 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 8 0 0 8 % H
% Ile: 8 8 0 8 0 0 0 0 0 0 8 0 8 8 8 % I
% Lys: 8 0 8 0 15 8 43 8 0 50 8 8 0 0 15 % K
% Leu: 50 0 0 0 0 0 0 8 8 8 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 15 0 0 0 15 0 0 8 29 15 8 0 % N
% Pro: 0 0 0 0 0 8 8 8 15 0 8 0 0 29 50 % P
% Gln: 0 0 8 0 50 8 8 8 8 8 0 0 0 8 8 % Q
% Arg: 0 0 50 65 22 50 15 0 0 0 43 43 22 0 0 % R
% Ser: 0 8 8 0 0 0 0 43 0 0 0 0 0 8 8 % S
% Thr: 8 22 8 8 0 0 0 0 8 0 0 0 0 15 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 8 8 15 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _